bsm-30248A-PACIFIC BLUE

DATASHEET

Host: Rat

Target Protein: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Clonality: Monoclonal

Isotype: IgG2a/Kappa

Entrez Gene: 12494

Swiss Prot: P56528

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

This gene encodes a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Knockout mice deficient for this gene display altered humoral immune responses. In addition, knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors. [provided by RefSeq, Sep 2015]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 237l staining volume)

Predicted Molecular Weight: 34

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.